Peer-Reviewed Science
Nature Metabolism 2019 Cover Picture
by Juan Cruz Landoni and Markus Innilä
Mitochondrial DNA (mtDNA) replication stress in mtDNA mutator mice causes DNA damage (yellow dots) in spermatoid progenitors (turquoise nuclei), thus suggesting that defects in nuclear genome maintenance might be a unified mechanism for mouse progerias.
Overactive mitochondrial DNA replisome causes neonatal heart failure via ferroptosis
BioRxiv preprint
Juan C. Landoni, Tuomas Laalo, Steffi Goffart, Riikka Kivelä, Karlo Skube, Anni I. Nieminen, Sara A. Wickström, James Stewart, Anu Suomalainen
Dissertationes Scholae Doctoralis Ad Sanitatem Investigandam Universitatis Helsinkiensis
Doctoral Thesis - Juan Cruz Landoni
IMPDH2: a new gene associated with dominant juvenile-onset dystonia-tremor disorder
European Journal of Human Genetics
​Anna Kuukasjärvi*, Juan C. Landoni*, Jyrki Kaukonen, Mika Juhakoski, Mari Auranen, Tommi Torkkeli, Vidya Velagapudi & Anu Suomalainen
*Shared first authorship
Defects in mtDNA replication challenge nuclear genome stability through nucleotide depletion and provide a unifying mechanism for mouse progerias
Nature Metabolism (2019)
Riikka H. Hämäläinen, Juan C. Landoni, Kati J. Ahlqvist, Steffi Goffart, Sanna Ryytty, M. Obaidur Rahman, Virginia Brilhante, Katherine Icay, Sampsa Hautaniemi, Liya Wang, Marikki Laiho & Anu Suomalainen
Quantitative solid-phase assay to measure deoxynucleoside triphosphate pools
Biology Methods and Protocols (2018)
A complex genomic locus drives mtDNA replicase POLG expression to its disease-related nervous system regions
EMBO Molecular Medicine (2018)
Joni Nikkanen, Juan Cruz Landoni, Diego Balboa, Maarja Haugas, Juha Partanen, Anders Paetau, Pirjo Isohanni, Virginia Brilhante, Anu Suomalainen
Structural Insights into Creatine Transport from Novel Disease Mutation
MSc Thesis, unpublished manuscript
Juan Cruz Landoni, Joni Nikkanen, Liliya Euro, Anu Suomalainen
Science Communication
Pintó Colaborar
Dato Encerrado Podcast
Guest in the popular science podcast Dato Encerrado (In Spanish), talking about mitochondria, their evolution and how they impact everything we know and don't.
Mitochondrial Musical (Rap Cover)
Mitochondrial origins, function, disease and research through a Hamilton-inspired musical performance.
Presented and winner of the Global Young Scientists Summit Video Competition, Singapore 2021
El Gato y La Caja
Hay Tabla
Itrio 39
A short story about the adventures and disadventures behind the discovery of the element Yttrium, for the Hay Tabla initiative. [Spanish]
Poster by Juama Garrido
Other Science Outreach Participation
Dato Encerrado Podcast
Guest appearance in The Science Basement Podcast, talking about mitochondrial biology, evolution and disease.
The Science Basement Podcast
Guest appearance in The Science Basement Podcast, to talk about mitochondria, mitochondrial disease, and play some TSB-styled games.
Writer and Editor of MyScience.fi
MyScience.fi was an online scicomm magazine aimed at youth interested in science and technology. It ceased to update in June 2016.